The fundamental problem with high-energy radiation is that it is destructive to chemical bonds -- the higher the energy, the more generally destructive it is. Short UV is capable of breaking most weaker chemical bonds, and with only the strongest bonds to choose from, it is difficult to imagine substances or materials capable of storing genetic information or bio-available energy that would not break down rapidly on exposure. X-rays are even more energetic, and gamma rays more energetic still, thus able to break almost any kind of chemical bond. X-ray or gamma ray "illumination" at anything like the intensity of visible light on the surface of Mars (quite a bit dimmer than on Earth) would destroy any chemical-based life. Short UV is sort of on the threshold -- conceivable that life could evolve to handle it, but unlikely that the first forms of life could. So the further evolution of primitive life under such illumination would be nipped in the bud.
Advanced, Earth-like life forms, starting from a less resistant genetic population and subjected over time to increasing radiation levels, have proven capable of adapting to surprisingly energetic radiation. But they had a "leg up", so to speak, in that they evolved to a fairly advanced stage with metabolic and genetic flexibility/adaptability before being stressed with that radiation on top of everything else. Prebiotic evolution without an ozone shield would be more difficult -- Earth's oceans are probably what made it possible here, and if Mars indeed had oceans at one time, it may have happened there as well. It's a question of whether the loss of deep water on Mars was too fast for primitive organisms to adapt to more energetic radiation. At this point, we don't know, but if it was, it's certainly less likely that life would re-evolve from prebiotic conditions afterwards. Given infinite time, of course, even the unlikely becomes inevitable, but Mars hasn't had anything like infinite time -- has it had time enough ? We just don't know (yet).